This comedy follows two codependent East Village, New York girls, Olivia and Nicole, on the verge of eviction and existential crisis. They're struggling artists, living in a Bohemian apartment. Their electricity has been turned off and they've begun an ill-advised juice fast. To top it all off, they're out of money and too "talented" to come up with the rent. To solve their problems they go to L.A. to visit Nicole's wealthy aunt, Kimberley, the host of a popular reality TV talent show. As Kimberley convinces the girls to audition, the girls struggle to maintain their friendship as Olivia begins to realize she may not be as dependent on Nicole as she once believed.

In 1958, in New York City, the upper class Diane Arbus is a frustrated and lonely woman with a conventional marriage with two daughters. Her husband is a photographer sponsored by the wealthy parents of Diane, and she works as his assistant. When Lionel Sweeney, a mysterious man with hypertrichosis (a.k.a. werewolf syndrome, a disease that causes excessive body hair), comes to live in the apartment in the upper floor, Diane feels a great attraction for him and is introduced to the world of freaks and marginalized people, falling in love with Lionel.